Please use this identifier to cite or link to this item: http://prr.hec.gov.pk/jspui/handle/123456789/2041
Full metadata record
DC FieldValueLanguage
dc.contributor.authorUDDIN, ALA-
dc.date.accessioned2017-12-11T05:51:59Z-
dc.date.available2017-12-11T05:51:59Z-
dc.date.issued2011-
dc.identifier.uri http://prr.hec.gov.pk/jspui/handle/123456789//2041-
dc.description.abstractThis dissertation deals with phytochemical and bioactivities studies on indigenous medicinal plants; Maytenus royleanus (Celastraceae) (Part A), Ficus faveolata (Moraceae) (Part B) and additional miscellaneous part C (Cyclotetrapeptides from Aspergillus ochraceopetaliformis). Part-A Part A deals with phytochemical and bioactivities studies on the chemical constituents of the roots of Maytenus royleanus. The systematic phytochemical studies have led to the isolation and structure elucidation of three new compounds (1-3). In addition seven known compounds (4-10) have also been isolated for the first time from this species. Structures have been elucidation by advanced spectroscopic techniques. Royleanine A (1) 1β,2β,5β,7β,8β,11-Hexaacetoxy-4-hydroxy-3α,15-[2',3'-dimethyl-3'(5''-carboxy- 2''-pyridyl)-propanoic acid] dicarbolactone-dihydro-agarofuran Royleanine B (2) 1β,2β,5β,7β,8β,11-Hexaacetoxy-3α,15-[2'-methyl-4'(5''-carboxy-2''- pyridyl)-butanoic acid] dicarbolactone-dihydroagarofuran Royleanine C (3) 1β,2β,5β,7β,8β,11-Hexaacetoxy-3α,15-[2'-methyl-2'β-benzoate-4'(4''- carboxy-2''-pyridyl)-butanoic acid] dicarbolactone-dihydroagarofuran Salaspermic acid (4) Orthosphenic acid (5) 3α,22β-Dihydroxyolean-12-en-29-oic acid (6) Oleuropein (7) Ligutroside (8) Quercetin (9) β-Sitosterol-3-O-β-D-glycopyrannoside (10) Part-B Part B deals with isolation and characterization of chemical constituents from Ficus faveolata. Five compounds were isolated from the stem methanolic extract of Ficus faveolata; two of them are new (11, 12) and three known compounds (13-15) hitherto unreported from this source. Their structures have been elucidated by spectroscopic techniques. Ficusonic acid (11) 3β,21β-Dihydroxy-olean-12-en-29-oic acid Ficusonolide (12) 3α-Hydroxylean-12-en-29,19α-olide Gallocatechine (13) β-Sitosterol-3-O-β-D-glycopyrannoside (14) 3β,22β-Dihydroxyolean-12-en-29-oic acid(15) Part-C Part C is the miscellaneous section which describes the isolation and characterization of two new Cyclotetrapeptides; ochrine A (16) and ochrine B (17) from the fungal strain Aspergillus ochraceopetaliformis collected from Hawaii shallow water sediment. Their structures have been elucidated by modern spectroscopic techniques.en_US
dc.description.sponsorshipHigher Education Commission, Pakistanen_US
dc.language.isoenen_US
dc.publisherUNIVERSITY OF PESHAWARen_US
dc.subjectNatural Sciencesen_US
dc.subjectChemistry & allied sciencesen_US
dc.subjectChemistryen_US
dc.titlePHYTOCHEMISTRY AND BIOACTIVITY OF MAYTENUS ROYLEANUS AND FICUS FAVEOLATAen_US
dc.typeThesisen_US
Appears in Collections:PhD Thesis of All Public / Private Sector Universities / DAIs.

Files in This Item:
File Description SizeFormat 
1596S-0.pdfTable of Contents109.38 kBAdobe PDFView/Open
1596S.pdfComplete Thesis7.65 MBAdobe PDFView/Open


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.