Physico-Chemical Characterization of Normal Human Blood

Abstract

An attempt has been made to determine normal values for some of the important biochemical parameters of blood of apparently healthy, Pakistani subjects. These values have been compared to those reported in the literature with the objective to formulate recommendations as to whether the normal reference values used in our laboratories which have been derived from the study of subjects in the economically developed countries of the world, with different socio-cultural and genetic background apply to our population. The results of our studies show that: 1. Haemoglobin and packed cell volume are low in all the age groups from birth to 23year. 2. The upper limit for SGOT in our subjects is significantly lower than that reported in the literature. 3. The lower limit for serum sodium and potassium are 130 and 3.1 m.Eqt/litre as compared to the 135 and 3.5 in literature. The value of potassium is also higher as 6.0 m.Eqt/litre in children than that reported. 4. The values for cholesterol, triglyceride and total lipids are 188+31, 98+27 and 640+160 mg/dl respectively showing significant differences in the values for cholesterol and triglyceride. 5. For uric acid and creatinine no statistically significant differences are found although mean uric acid is slightly higher in both males and females in our subjects. 6. The range for blood urea also showed a significant difference. As compared to the 20-40 mg/dl reported value for range, it was found to be 13-30 mg/dl